Isaiah 66:16

For by fire and by his sword will the LORD plead with all flesh: and the slain of the LORD shall be many.

For by fire, and by his sword, will the Lord plead with all flesh,.... With the Mahometans, the Turks, the Ottoman empire, against whom he will call for a sword, and will rain upon them fire and brimstone, signified by Gog and Magog, Ezekiel 38:22 and with the other antichristian powers at the battle of Armageddon; and when the fourth vial will be poured upon the sun, and men will be scorched with fire; see Revelation 16:8:

and the slain of the LORD shall be many; that is, those that will be slain by the Lord, both in the attempt of the Turks to recover the land of Canaan out of the hands of the Jews, possessed of it; whose numbers of slain will be so many, that the burying of them will last seven months, Ezekiel 39:12 and in the battle between the Christian princes, Christ at the head of them, and the antichristian armies, led on by the beast and the kings of the earth; when the fowls of the air will be invited to the great supper of the Lord, to eat the flesh of kings, captains, and mighty men, so great will the slaughter be,

Revelation 19:17, see also Isaiah 11:13.