Isaiah 1:15
And when ye spread forth your hands, I will hide mine eyes from you: yea, when ye make many prayers, I will not hear: your hands are full of blood.
And when ye spread forth your hands,.... That is, in prayer, this being a prayer gesture: hence the Targum paraphrases it,
"and when the priests spread out their hands to pray for you.''
I will hide mine eyes from you; will not look upon them, nor regard their prayer; see Lamentations 3:42
yea, when ye make many prayers; as the Scribes and Pharisees did in Christ's time, and thought to be heard for their much speaking, like the Gentiles, Matthew 6:7
I will not hear; so as to give an answer, or fulfil their requests: the reason follows,
your hands are full of blood; of the prophets of the Lord, of Christ and his followers, whom they put to death.