John Gill's  Exposition of the Bible 

Jeremiah 51:22

With thee also will I break in pieces man and woman; and with thee will I break in pieces old and young; and with thee will I break in pieces the young man and the maid;

And with thee also will I break in pieces man and woman,.... Or, "have broken"; having no respect to any sex, and to the propagation of posterity:

and with thee will I break in pieces old and young; not sparing men of any age, however useful they might be, the one for their wisdom, the other for their strength:

and with thee will I break in pieces the young man and the maid; who by procreation of children might fill and strengthen commonwealths.